Seahawks vs. Titans prediction, odds, spread, injuries, trends for NFL Week 16

A full betting preview for the Seattle Seahawks' Week 16 matchup against the Tennessee Titans.
Dec 18, 2023; Seattle, Washington, USA; Seattle Seahawks running back Kenneth Walker III (9) rushes
Dec 18, 2023; Seattle, Washington, USA; Seattle Seahawks running back Kenneth Walker III (9) rushes / Joe Nicholson-USA TODAY Sports

The Seattle Seahawks snapped their four-game losing streak last week with an impressive 20-17 win over the Philadelphia Eagles. The Seahawks will try to their strengthen playoff chances against the Tennessee Titans on Christmas Eve.

The Titans suffered their second overtime loss in their past three game as they lost 19-16 to the Houston Texans. Tennessee also lost rookie quarterback Will Levis to an ankle injury, which means the Seahawks could see Ryan Tannehill under center.

The Seahawks are 2.5-point road favorites over the Titans. Below, we will break down this Week 16 matchup and give our best bet!

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Seahawks vs. Titans Odds, Spread and Total

Seahawks vs. Titans Betting Trends

  • The Seahawks are 5-2 against the spread (ATS) on the road this season
  • The UNDER is 4-1 in Seattle’s last five games vs. AFC opponents
  • Tennessee is 2-5 ATS in its last seven games
  • The UNDER is 4-1 in the Titans’ past five games vs. NFC opponents

Seahawks vs. Titans Injury Reports

Seahawks Injury Report

  • Devon Witherspoon - CB - Questionable
  • Jamal Adams - S - Questionable
  • Dee Eskridge - WR - Questionable

Titans Injury Report

  • Jeffery Simmons - DT - Questionable
  • Will Levis - QB - Questionable
  • Josh Whyle - TE - Questionable
  • Kyle Philips - WR - Questionable
  • Sean Murphy-Bunting - CB - Questionable

Seahawks vs. Titans How to Watch

  • Date: Sunday, Dec. 24
  • Game Time: 1 p.m. EST
  • Venue: Nissan Stadium
  • How to Watch (TV): CBS
  • Seahawks Record: 7-7
  • Titans Record: 5-9

Seahawks vs. Titans Key Players to Watch

Seattle Seahawks

Kenneth Walker III: The second-year running back had a solid bounce-back game against the Eagles in Week 15. Walker III was a one-man wrecking crew in the backfield, totaling 112 yards and a rushing touchdown on 22 touches. The 23-year-old Walker will try to capitalize on that performance heading into this week’s game against the Titans.

Tennessee Titans

DeAndre Hopkins: The veteran wide receiver is coming off a rough game against the Texans last week, where he had two receptions (nine targets) for 21 yards. This season, Hopkins has been one of the lone bright spots on the offense, with 59 receptions for 919 yards and six TDs. He will hope to get back on track this week with potentially a new quarterback under center as Will Levis is dealing with an ankle sprain.

Seahawks vs. Titans Prediction and Pick

The Seahawks salvaged their season last week with a 20-17 win over the Eagles, snapping their four-game losing streak. Seattle got a solid performance from backup QB Drew Lock, who made his second straight start for Geno Smith. Lock completed 22-of-33 passes for 208 yards and a touchdown.

Smith should be back on the field for this week’s game against a Titans’ pass defense that has allowed 226.4 yards per game (22nd in the NFL). If Walker can run the ball like he did against the Eagles, it will help the Seahawks’ passing game, which didn’t have a ton of explosive plays in Week 16.

As for the Titans, I don’t see their passing game being successful, whether they start Levis or Ryan Tannehill. Statistically, the Seahawks’ pass defense hasn’t been great, but their front four can get pressure. 

Therefore, Tennessee’s best offense is star running back Derrick Henry, who hasn’t looked like the same RB we’ve seen over the past few seasons. The Seahawks haven’t played great on the road this season (2-5), but they are the better team heading into this week’s game. 

Game odds refresh periodically and are subject to change.